Estrogen-secreting adrenocortical carcinoma

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A case of estrogen-secreting adrenocortical carcinoma with subclinical Cushing's syndrome.

A 25-year-old man was found to have a large right adrenal mass detected by abdominal echography and computed tomography, and presented with a mild gynecomastia. Endocrine study showed increased serum concentrations and urinary excretion of estrogens and dehydroepiandorosterone sulfate (DHEA-S). The patient had no Cushingoid features but autonomous cortisol secretion, compatible with the diagnos...

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Adrenocortical carcinoma secreting cortisol, androgens and aldosterone: a case report

INTRODUCTION Adrenocortical carcinoma is a rare malignancy with a poor prognosis and presents with mass effects and less often with signs of hormone excess (approximately 60% of all adrenocortical carcinoma's). Hormonally active adrenocortical carcinomas most commonly secrete cortisol while the co-secretion of multiple steroid hormones is rare. CASE PRESENTATION We report the case of a 59 yea...

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Androgen secreting adrenocortical tumours.

BACKGROUND Androgen secreting adrenocortical tumours are rare in children and the determination of their malignant potential can be difficult. OBJECTIVES To assess the presentation, histology, and clinical behaviour of these tumours. SETTING Two tertiary referral centres. STUDY DESIGN Retrospective analysis of children diagnosed with an androgen secreting adrenocortical tumour between 197...

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Outcomes after resection of cortisol-secreting adrenocortical carcinoma.

BACKGROUND We sought to define the impact of cortisol-secreting status on outcomes after surgical resection of adrenocortical carcinoma (ACC). METHODS The U.S ACC group database was queried to identify patients who underwent ACC resection between 1993 and 2014. The short-term and long-term outcomes were assessed. RESULTS The incidence of all functional and cortisol-secreting tumors was 40.6...

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Aldosterone-secreting adrenocortical adenoma in children

Aldosterone-secreting adrenocortical adenoma is an unusual cause of secondary hypertension in childhood. We describe an eight year-old female child who presented clinically with weakness of lower limbs, headache and hypertension. Thorough clinical, laboratory and radiological evaluations confirmed the diagnosis of hyperaldosteronism due to a left adrenocortical adenoma. Left adrenalectomy after...

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ژورنال

عنوان ژورنال: Yeungnam University Journal of Medicine

سال: 2019

ISSN: 2384-0293

DOI: 10.12701/yujm.2019.00017